Transcriptional repression of the GnRH1 gene by Pur-B
نویسندگان
چکیده
1 REGULATION OF GONADOTROPIN RELEASING 1 HORMONE 1 GENE TRANSCRIPTION BY MEMBERS OF 2 THE PURINE-RICH ELEMENT BINDING PROTEIN FAMILY 3 Sheng Zhao, Robert J. Kelm, Jr., and Russell D. Fernald 4 5 1 Department of Biology & Neuroscience, Stanford University, Stanford, California 94305-5020 6 Department of Medicine, University of Vermont College of Medicine, Burlington, VT 05405 7 8
منابع مشابه
Regulation of gonadotropin-releasing hormone-1 gene transcription by members of the purine-rich element-binding protein family.
Gonadotropin-releasing hormone-1 (GnRH1) controls reproduction by stimulating the release of gonadotropins from the pituitary. To characterize regulatory factors governing GnRH1 gene expression, we employed biochemical and bioinformatics techniques to identify novel GnRH1 promoter-binding proteins from the brain of the cichlid fish, Astatotilapia burtoni (A. burtoni). Using an in vitro DNA-bind...
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تاریخ انتشار 2009